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Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness

Wenjun Xia,Fei Liu,Duan Ma

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 137-142 doi: 10.1007/s11684-016-0449-8

Abstract: Hereditary hearing loss is divided into syndromic hearing loss (associated with other anomalies) andnon-syndromic hearing loss (not associated with other anomalies).Approximately 80% of genetic deafness is non-syndromic.On the basis of the frequency of hearing loss, hereditary non-syndromic hearing loss can be divided intohigh-, mid-, low-, and total-frequency hearing loss.

Keywords： hereditary non-syndromic hearing loss     mid-frequency hearing loss     deafness genes    

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Ionically Imprinting-Based Copper (Ⅱ) Label-Free Detection for Preventing Hearing Loss Article

Huan Wang, Hui Zhang, Xiaoli Zhang, Hong Chen, Ling Lu, Renjie Chai

Engineering doi: 10.1016/j.eng.2023.09.001

Abstract: ion (Cu2+) may cause severe health problems, such as hair cell apoptosis and the resultant hearingloss.IIHBs are promising candidates for Cu2+ detection, particularly for the prevention of hearingloss.

Keywords： Structural color     Microfluidics Ionic imprinting     Label-free detection     Hearing loss    

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Panoramic variation analysis of a family with neurodevelopmental disorders caused by biallelic loss-of-function

Frontiers of Medicine doi: 10.1007/s11684-023-1006-x

Abstract: Notably, the biallelic loss-of-function variants of TMEM141 were responsible for syndromic ID.

Keywords： neurodevelopmental disorder     autosomal recessive intellectual disability     consanguinity     spastic paraplegia     hearingloss     TMEM141    

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Alternative splicing of inner-ear-expressed genes

Yanfei Wang,Yueyue Liu,Hongyun Nie,Xin Ma,Zhigang Xu

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 250-257 doi: 10.1007/s11684-016-0454-y

Abstract: Consequently, deficits in alternative splicing have been shown to cause hearing loss, as we can observeFurther investigation is also needed to clarify the mechanism of hearing loss caused by alternative splicing

Keywords： alternative splicing     inner ear     hearing loss     hair cells    

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Loss of liver kinase B1 causes planar polarity defects in cochlear hair cells in mice

Yuqin Men,Aizhen Zhang,Liwen Zhang,Yecheng Jin,Zhishuo Wang,Jing Zhao,Xiaolin Yu,Jian Zhang,Jiangang Gao

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 481-489 doi: 10.1007/s11684-016-0494-3

Abstract:

The tumor suppressor gene liver kinase B1 (LKB1), also called STK11, encodes a serine/threonine kinase. LKB1 plays crucial roles in cell differentiation, proliferation, and polarity. In this study, LKB1 conditional knockout mice (LKB1Pax2 CKO mice) were generated using Pax2-Cre mice to investigate the function of LKB1 in inner ear hair cells during early embryonic period. LKB1Pax2 CKO mice died perinatally. Immunofluorescence and scanning electron microscopy revealed that stereociliary bundles in LKB1Pax2 CKO mice were clustered and misoriented, respectively. Moreover, ectopic distribution of kinocilium bundles resulting from abnormal migration of kinocilium was observed in the mutant mice. The orientation of stereociliary bundles and the migration of kinocilia are critical indicators of planar cell polarity (PCP) of hair cells. LKB1 deficiency in LKB1Pax2 CKO mice thus disrupted hair cell planar polarity during embryonic development. Our results suggest that LKB1 is required in PCP formation in cochlear hair cells in mice.

Keywords： LKB1     stereociliary bundles     kinocilium     planar cell polarity     hearing     mice    

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Loss coefficient of nitrogenous non-point source pollution under various precipitation conditions

CHENG Hongguang, HAO Fanghua, REN Xiyan, YANG Shengtian, XIONG Wen, LEI Shaoping

Frontiers of Environmental Science & Engineering 2008, Volume 2, Issue 2,   Pages 230-235 doi: 10.1007/s11783-008-0043-7

Abstract: In this study, calibrations of non-point source (NPS) pollution models are performed based on Black RiverThe concept of NPS loss

Keywords： information     concept     non-point     historical real-time     sedimentation    

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Power fluctuation and power loss of wind turbines due to wind shear and tower shadow

Binrong WEN, Sha WEI, Kexiang WEI, Wenxian YANG, Zhike PENG, Fulei CHU

Frontiers of Mechanical Engineering 2017, Volume 12, Issue 3,   Pages 321-332 doi: 10.1007/s11465-017-0434-1

Abstract: the effects of wind shear and tower shadow on power output in terms of power fluctuation and power lossPower fluctuation and power loss due to wind shear and tower shadow are analyzed by performing theoreticalUnder steady wind conditions, power loss can be divided into wind farm loss and rotor loss.Wind farm loss is constant at 3α(3α−1)R2/(8By contrast, rotor loss is strongly influenced by the wind turbine control strategies and wind speed.

Keywords： wind turbine     wind shear     tower shadow     power fluctuation     power loss    

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Turnover and loss of nitrogenous compounds during composting of food wastes

YANG Yanmei, ZHANG Xiangfeng, YANG Zhifeng, XI Beidou, LIU Hongliang

Frontiers of Environmental Science & Engineering 2008, Volume 2, Issue 2,   Pages 251-256 doi: 10.1007/s11783-008-0042-8

Abstract: This study aimed to investigate the solid-phase nitrogen, water-soluble nitrogen, nitrogen loss togethercontent of the water-soluble nitrogen compounds in the compost greatly increased, the total nitrogen losssuggested that the control at the middle and late composting of thermophilic stage is the key to nitrogen loss
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Winner determination problem with loss-averse buyers in reverse auctions

Xiaohu QIAN, Min HUANG, Yangyang YU, Xingwei WANG

Frontiers of Engineering Management 2017, Volume 4, Issue 2,   Pages 212-220 doi: 10.15302/J-FEM-2017019

Abstract: novel winner determination problem in a multiple-object reverse auction in which the buyer involves loss-averseIn addition, the proposed model can effectively characterize the buyer’s loss-averse behavior.

Keywords： reverse auction     loss aversion     winner determination     improved ant colony algorithm    

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New US Rules Promise to Unlock Hearing Aid Availability

Mitch Leslie

Engineering 2022, Volume 14, Issue 7,   Pages 7-9 doi: 10.1016/j.eng.2022.05.008

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A novel energy loss model and optimization design of the coin chute flection curve

Qinghua LIANG, Jinqiu MO, Weizhong GUO

Frontiers of Mechanical Engineering 2012, Volume 7, Issue 1,   Pages 38-46 doi: 10.1007/s11465-012-0311-x

Abstract:

In this paper, we propose a novel design model based on the energy loss of the coin (ELM model) toTwo different kinds of energy loss models are analyzed according to dynamic characteristics of the coinpoints and end points derivatives as inputs, and the curve model is governed and affected by energy lossequations, allowing to minimize the total energy loss before the coin arrives at the detecting position, thus to reduce the energy loss and collisions between the coin and the flection, thus to improve the

Keywords： flection curve     B-spline     energy loss model (ELM model)     optimization design    

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Power system reconfiguration and loss minimization for a distribution systems using “Catfish PSO” algorithm

K Sathish KUMAR,S NAVEEN

Frontiers in Energy 2014, Volume 8, Issue 4,   Pages 434-442 doi: 10.1007/s11708-014-0313-y

Abstract: important ways to save electrical energy in the distribution system is network reconfiguration for losssuch a way that the radial structure of networks is maintained, all of the loads are energized, power lossfeeder reconfiguration is a complex nonlinear combinatorial problem since the status of the switches is non-differentiablereconfiguration (DFR) problem for a 33-bus and a 16-bus sample network, which effectively ensures the loss

Keywords： distribution system reconfiguration (DFR)     power loss reduction     catfish particle swarm optimization (catfish    

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Effect of mulching with maize straw on water infiltration and soil loss at different initial soil moistures

Yifu ZHANG,Hongwen LI,Jin HE,Qingjie WANG,Ying CHEN,Wanzhi CHEN,Shaochun MA

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 2,   Pages 161-170 doi: 10.15302/J-FASE-2016104

Abstract: soil erosion, and this study investigated the effect of straw mulching on water infiltration and soil lossIncreasing initial SWC can decrease soil infiltration and increase soil loss.straw mulching of 30% or more significantly enhanced water infiltration by over 31% and reduced soil loss

Keywords： infiltration     initial soil water content     rainfall simulation     soil loss     straw mulching    

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Effects of riparian vegetation patterns on the distribution and potential loss of soil nutrients: a case

Erhui GUO,Liding CHEN,Ranhao SUN,Zhaoming WANG

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 2,   Pages 279-287 doi: 10.1007/s11783-014-0667-8

Abstract: This study examines the impact of riparian vegetation patterns on water pollution due to soil nutrient lossdifferent distributions of soil nutrients along vegetation patterns and the potential risk of nutrient lossgrassland has higher levels of soil TN, TP, AN, and AP, and thus it may become a new source of nutrient loss

Keywords： riparian     vegetation patterns     soil nutrient distribution     nutrient loss     management    

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Low-carbohydrate diets lead to greater weight loss and better glucose homeostasis than exercise: a randomized

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 460-471 doi: 10.1007/s11684-021-0861-6

Abstract: After the interventions, LCD led to a larger weight loss than EX (−3.56±0.37 kg vs. −1.24±0.39 kg, loss and glucose homeostasis in people

Keywords： low-carbohydrate diet     obesity     nonalcoholic fatty liver disease     continuous glucose monitoring     mean sensor glucose    

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Title Author Date Type Operation

Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness

Wenjun Xia,Fei Liu,Duan Ma

Journal Article

Ionically Imprinting-Based Copper (Ⅱ) Label-Free Detection for Preventing Hearing Loss

Huan Wang, Hui Zhang, Xiaoli Zhang, Hong Chen, Ling Lu, Renjie Chai

Journal Article

Panoramic variation analysis of a family with neurodevelopmental disorders caused by biallelic loss-of-function

Journal Article

Alternative splicing of inner-ear-expressed genes

Yanfei Wang,Yueyue Liu,Hongyun Nie,Xin Ma,Zhigang Xu

Journal Article

Loss of liver kinase B1 causes planar polarity defects in cochlear hair cells in mice

Yuqin Men,Aizhen Zhang,Liwen Zhang,Yecheng Jin,Zhishuo Wang,Jing Zhao,Xiaolin Yu,Jian Zhang,Jiangang Gao

Journal Article

Loss coefficient of nitrogenous non-point source pollution under various precipitation conditions

CHENG Hongguang, HAO Fanghua, REN Xiyan, YANG Shengtian, XIONG Wen, LEI Shaoping

Journal Article

Power fluctuation and power loss of wind turbines due to wind shear and tower shadow

Binrong WEN, Sha WEI, Kexiang WEI, Wenxian YANG, Zhike PENG, Fulei CHU

Journal Article

Turnover and loss of nitrogenous compounds during composting of food wastes

YANG Yanmei, ZHANG Xiangfeng, YANG Zhifeng, XI Beidou, LIU Hongliang

Journal Article

Winner determination problem with loss-averse buyers in reverse auctions

Xiaohu QIAN, Min HUANG, Yangyang YU, Xingwei WANG

Journal Article

New US Rules Promise to Unlock Hearing Aid Availability

Mitch Leslie

Journal Article

A novel energy loss model and optimization design of the coin chute flection curve

Qinghua LIANG, Jinqiu MO, Weizhong GUO

Journal Article

Power system reconfiguration and loss minimization for a distribution systems using “Catfish PSO” algorithm

K Sathish KUMAR,S NAVEEN

Journal Article

Effect of mulching with maize straw on water infiltration and soil loss at different initial soil moistures

Yifu ZHANG,Hongwen LI,Jin HE,Qingjie WANG,Ying CHEN,Wanzhi CHEN,Shaochun MA

Journal Article

Effects of riparian vegetation patterns on the distribution and potential loss of soil nutrients: a case

Erhui GUO,Liding CHEN,Ranhao SUN,Zhaoming WANG

Journal Article

Low-carbohydrate diets lead to greater weight loss and better glucose homeostasis than exercise: a randomized

Journal Article